Systemic Sclerosis
Systemic sclerosis (SSc) is a multisystem autoimmune disease involving vasculopathy and immune activation that leads to the deposition of extracellular matrix and the development of fibrosis, resulting in cardinal clinical problems. Systemic Sclerosis – Recent Advances and New Perspectives provides a comprehensive overview of the pathophysiology, diagnosis, and specific management of the clinical manifestations of […]
RNA Therapeutics
RNA therapies evolved as economical and widely applicable individualized treatment solutions. Novel RNA-based therapeutic vaccines (e.g., against SARS-CoV-2 infection) have been proven to be safe and effective, and many of them are approved by the United States Food and Drug Administration (FDA). This book presents distinct classes of RNA therapeutics, ranging from single-stranded antisense oligonucleotides […]
Reactive Oxygen Species
Reactive Oxygen Species (ROS) are molecules generated naturally during cellular metabolic processes. They act as signaling agents that oversee specific biochemical pathways, playing a vital role in cell function and survival. However, an imbalance in ROS signaling or excessive ROS production can have harmful effects on the pathophysiology of diseases. ROS are crucial to cell […]
Pleura
This book provides the thoracic community and pleura experts with an up-to-date surgical vision of pleura pathology. It provides in-depth knowledge and a better understanding of the indications, positioning techniques, and management of chest drains and indwelling catheters, which are commonly utilized in the management of the pleural disease. The book addresses complex topics such […]
Pathophysiology
Pathophysiology is the convergence of pathology (the discipline of observed changes in a diseased state) with physiology (the mechanisms of systems operation). It represents the functional changes that occur because of injury or disease. This volume provides state-of-the-art up-to-date literature reviews on pathophysiological processes in a number of disease states. The book is organised methodically […]
Pain Management – From Acute to Chronic and Beyond
With more than 230 million surgical procedures performed annually worldwide, and 30% or more of people affected by chronic pain globally, pain management is consistently a top priority. Its personal and social burden is enormous and thus much literature and research focuses on pain medicine. Along with the evolution of precision medicine, today’s typical pain […]
Oncology Critical Care
According to the American Cancer Society, more than 1.6 million people will be diagnosed with cancer during this year. Outcomes have steadily risen over the last several decades with the advent of newer therapies. As outcomes have improved, more and more cancer patients are developing critical illness. In the not-too-distant past, patients with active malignancy […]
Occupational Therapy
Occupational therapy is a health care specialty with a deep focus on client-centered and holistic rehabilitation to improve the individual’s occupational performance, quality of life and well-being through participation in meaningful and purposeful activities. This new book presents the importance of the therapeutic and creative use of activity in different populations, which is one of […]
Normal and Malignant B-Cell
Normal and Malignant B-Cell is a collection of harmonious chapters contributed by different authors. This book sets out to describe the B-cell during different stages of ontogeny and the molecular mechanisms of its antigen receptor diversity. It also discusses the main clinical and etiopathogenic aspects when it is transformed into a malignant cell. The book […]
New Developments in HIV Treatments
The book introduces and discusses new drugs for radical cure of HIV/AIDS. It also discusses the problems and challenges of these treatments. Chapters address problems related to the use of antiplatelet therapy in HIV treatment, gene-based therapies as the most promising candidates for the ultimate cure of infection, obesity as an emerging public health problem […]
